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Genetic polymorphisms in DNA repair genes XRCC1 and 3 are associated with increased risk of breast cancer in Bangladeshi population.

Breast cancer research and treatment - 1 Aug 2020

Howlader Nupur Rani, Rahman Md Mostafizur, Hossain Md Amir, Sultana Razia, Hossain Syed Mozammel, Mazid Md Abdul, Rahman Md Mustafizur

Abstract excerpt

BACKGROUND: Genetic polymorphisms in DNA repair genes, XRCC1 (Arg399Gln) and XRCC3 (Thr241Met), may affect their DNA repair capacity leading to individual variation in breast cancer susceptibility among Bangladeshi females. METHODS: The case-control study comprised 121 breast cancer patients and 133 healthy controls. Genomic DNA isolated from peripheral blood was genotyped for target SNPs using PCR-RFLP method....

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PMID: 32562117
DOI: 10.1007/s10549-020-05738-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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