Article
Association of XRCC1 gene polymorphisms with breast cancer susceptibility in Saudi patients.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Al Mutairi Fatima Masoud, Alanazi Mohammed, Shalaby Manal, Alabdulkarim Huda A, Pathan Akbar Ali Khan, Parine Narasimha Reddy
Abstract excerpt
BACKGROUND: X-ray repair cross-complementing group 1 (XRCC1) plays a key role in the base excision repair pathway, as a scaffold protein that brings together proteins of the DNA repair complex. XRCC1 is reported to be a candidate influence on cancer risk. The aim of our present study was to assess the association of rs1799782 (Arg194Trp) and rs25487 (Arg399Gln) XRCC1 gene polymorphisms with breast cancer in the...
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