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Article

Impact of XRCC1 genetic variants on its tissue expression and breast cancer risk: A case-control study.

Environmental and molecular mutagenesis - 1 Aug 2021

Abdel Ghafar Muhammad Tarek, El-Rashidy Mohamed Ali, Gharib Fatma, Al-Ashmawy Ghada Mohammad

Abstract excerpt

X-ray repair cross-complementing group 1 (XRCC1), a coordinator protein of the DNA repair complex, is thought to be involved in cancer progression. This case-control study aimed to investigate the association of two biallelic single-nucleotide polymorphisms (SNPs; Arg399Gln, Arg194Trp) of the XRCC1 gene with its tissue expression level and breast cancer (BC) risk in Egyptian women. This study included 100 BC...

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Identifiers

PMID: 34331480
DOI: 10.1002/em.22456

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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