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Article

Association between XRCC3 Thr241Met Polymorphism and Risk of Breast Cancer: Meta-Analysis of 23 Case-Control Studies.

Medical science monitor : international medical journal of experimental and clinical research - 25 Oct 2015

Chai Fan, Liang Yan, Chen Li, Zhang Fan, Jiang Jun

Abstract excerpt

BACKGROUND: Studies have shown that gene and environmental factors, such as BRCA1/2 mutations, ionized radiation, and chemical carcinogens, are related with breast cancer. X-ray repair cross-complementing group 3 (XRCC3) is involved in homologous repair of double DNA breaks. It was reported that Thr241Met single-nucleotide polymorphism (SNP) in XRCC3 is associated with increased risk of breast cancer. However,...

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Identifiers

PMID: 26498491
DOI: 10.12659/msm.894637
PMCID: PMC4627365

Genes

XRCC3
BRCA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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