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Article

XRCC1 Arg399Gln, Arg194Trp and Arg280His polymorphisms in breast cancer risk: a meta-analysis.

Mutagenesis - 1 Jul 2009

Huang Yongsheng, Li Linguo, Yu Long

Abstract excerpt

X-ray repair cross-complementing group 1 (XRCC1) plays an important role in base excision and single-strand break repair, as a scaffold protein that brings together proteins of the DNA repair complex, and appears to be a candidate for cancer risk. However, studies on the association between polymorphisms in this protein and cancer have yielded conflicting results. We performed a meta-analysis to investigate the...

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Identifiers

PMID: 19465687
DOI: 10.1093/mutage/gep013

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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XRCC1 Arg399Gln, Arg194Trp and Arg280His polymorphisms in breast cancer risk: a meta-analysis.PMID 19465687Read ↗

XRCC1 gene polymorphisms and breast cancer risk in different populations: a meta-analysis.Semantic proximity Read ↗

Polymorphism of XRCC1 (at codon 399) and susceptibility to breast cancer, a meta-analysis of the literatures.Semantic proximity Read ↗

XRCC1 Gene Polymorphisms and Breast Cancer Risk: A Systematic Review and Meta- Analysis Study.Semantic proximity Read ↗

XRCC1 Arg399Gln gene polymorphism and breast cancer risk: a meta-analysis based on case-control studies.Semantic proximity Read ↗

Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms with the risk of breast cancer: a case-control study in Egypt.Semantic proximity Read ↗

XRCC1 polymorphisms and cancer risk: a meta-analysis of 38 case-control studies.Semantic proximity Read ↗

XRCC1 Arg399Gln polymorphism confers risk of breast cancer in American population: a meta-analysis of 10846 cases and 11723 controls.Semantic proximity Read ↗

Assessment of the Link between XRCC1 Arg399Gln Polymorphism and Breast Cancer: a Meta-Analysis in a Single Ethnic Group.Semantic proximity Read ↗

Association of XRCC1 gene polymorphisms with breast cancer susceptibility in Saudi patients.Semantic proximity Read ↗

Impact of XRCC1 genetic variants on its tissue expression and breast cancer risk: A case-control study.Semantic proximity Read ↗

A prospective study of XRCC1 (X-ray cross-complementing group 1) polymorphisms and breast cancer risk.Semantic proximity Read ↗

Polymorphisms in DNA repair gene XRCC1 and increased genetic susceptibility to breast cancer.Semantic proximity Read ↗

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