Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populations

17 Jun 2020

Abstract excerpt

Many high-grade serous carcinomas (HGSCs) likely originate in the distal region of the Fallopian tube's epithelium (TE) before metastasizing to the ovary. Unfortunately, molecular mechanisms promoting malignancy in the distal TE are obfuscated, largely due to limited primary human TE gene expression data. Here we report an in depth bioinformatic characterization of 34 primary TE mRNA-seq samples. These samples...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer-related molecular mechanisms research
Share to Ovarian cancer diagnosis and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32555344
DOI: 10.1038/s41598-020-66556-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populationsPMID 32555344Read ↗

WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populationsSemantic proximity Read ↗

A Rare Multipotent Peg-like Epithelial Cell is a Candidate Cell-of-Origin for High-Grade Serous Ovarian CancerSemantic proximity Read ↗

Single-cell Transcriptomics Identifies Gene Expression Networks Driving Differentiation and Tumorigenesis in the Human Fallopian TubeSemantic proximity Read ↗

Integrated Human Transcriptomics Identifies Fallopian Tube Progenitors as Plausible Precursors of High-Grade Serous Ovarian CancerSemantic proximity Read ↗

Single-cell transcriptomics identifies gene expression networks driving differentiation and tumorigenesis in the human fallopian tubeSemantic proximity Read ↗

Lineage-Specific Epigenomic Mapping of Proximal and Distal Fallopian Tube Epithelium Reveals Mesenchymal/Wnt-Driven Tumor Phenotype DiversificationSemantic proximity Read ↗

Rete Ovarii Epithelial Cells as an Unappreciated Cell of Origin for Pelvic and Ovarian High-Grade Serous CarcinomaSemantic proximity Read ↗

In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cellsSemantic proximity Read ↗

Aged and BRCA -Mutated Stromal Cells Drive Epithelial Cell TransformationSemantic proximity Read ↗

3D multi-omic mapping of whole nondiseased human fallopian tubes at cellular resolution reveals a large incidence of ovarian cancer precursorsSemantic proximity Read ↗

Single Cell Transcriptomics identifies a WNT7A-FZD5 Signaling Axis that maintains Fallopian Tube Stem Cells in Patient-derived OrganoidsSemantic proximity Read ↗

Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.