Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insights into the role of the JAK/STAT signaling pathway in graft- versus -host disease

1 Jan 2020

Abstract excerpt

Allogeneic hematopoietic transplantation (allo-HCT) is a curative therapy for a variety of hematologic malignancies, primarily through immune-mediated clearance of malignant cells. This graft- versus-leukemia (GvL) effect is mediated by alloreactive donor T-cells against recipient malignant cells. Unfortunately, graft versus host disease is a potentially lethal complication of this procedure, also mediated by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Immune Cell Function and Interaction
Share to Mesenchymal stem cell research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32537114
DOI: 10.1177/2040620720914489

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insights into the role of the JAK/STAT signaling pathway in graft- versus -host diseasePMID 32537114Read ↗

JAK-STAT pathway in hematological malignancies: achievements, challenges and future perspectivesSemantic proximity Read ↗

Regulation of T cell homeostasis by JAKs and STATsSemantic proximity Read ↗

The JAK/STAT3 axis: A comprehensive drug target for solid malignancies.Semantic proximity Read ↗

Malignant JAK-signaling: at the interface of inflammation and malignant transformationSemantic proximity Read ↗

STAT Transcription Factors in T Cell Control of Health and Disease.Semantic proximity Read ↗

Janus Kinase-Signal Transducer and Activator of Transcription Inhibitors for the Treatment and Management of CancerSemantic proximity Read ↗

Series Introduction: JAK-STAT signaling in human diseaseSemantic proximity Read ↗

JAK/STAT in leukemia: a clinical updateSemantic proximity Read ↗

JAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indications.Semantic proximity Read ↗

Concise Review: Acute Graft-Versus-Host Disease: Immunobiology, Prevention, and TreatmentSemantic proximity Read ↗

STAT5 in Cancer and Immunity.Semantic proximity Read ↗

The JAK-STAT Pathway: Impact on Human Disease and Therapeutic InterventionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.