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Concise Review: Acute Graft-Versus-Host Disease: Immunobiology, Prevention, and Treatment

19 Dec 2012

Abstract excerpt

Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic stem cell transplant (AHSCT) associated with significant morbidity and mortality. This review focuses on the pathophysiology, clinical features, prevention, and treatment of acute GVHD. Specifically, we explain how new discoveries in immunology have expanded our understanding of GVHD, in which tissue damage from chemotherapy or...

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PMID: 23283494
DOI: 10.5966/sctm.2012-0115

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