Article
STAT Transcription Factors in T Cell Control of Health and Disease.
International review of cell and molecular biology - 1 Jan 2017
Goswami R, Kaplan M H
Abstract excerpt
The Jak-STAT pathway is one of many pleiotropic signaling pathways that plays an important role in organismal development and in response to changing environmental cues. As a key signaling cascade for cytokines and growth factors, Jak-STAT plays central role in the innate and adaptive immune system. Cytokines control the stability, commitment, and maturation of cytotoxic and helper T cells, parts of the adaptive...
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