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Article

STAT5 in Cancer and Immunity.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Apr 2016

Rani Aradhana, Murphy John J

Abstract excerpt

Signal transducers and activators of transcription 5 (STAT5a and STAT5b) are highly homologous proteins that are encoded by 2 separate genes and are activated by Janus-activated kinases (JAK) downstream of cytokine receptors. STAT5 proteins are activated by a wide variety of hematopoietic and nonhematopoietic cytokines and growth factors, all of which use the JAK-STAT signalling pathway as their main mode of...

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PMID: 26716518
DOI: 10.1089/jir.2015.0054

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