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Whole exome sequencing reveals the different responsiveness to Enterovirus 71 vaccination in Chinese children.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Aug 2020

Zhang Li, Yu Chengxiao, Ge Zijun, Tao Hong, Meng Fanyue, Xu Xin, Tian Ting, Song Ci, Hu Zhibin, Li Jingxin, Zhu Fengcai

Abstract excerpt

PURPOSE: To explore the molecular genetic mechanisms underlying different responsiveness to Enterovirus 71 (EV71) vaccine. METHODS: We recruited 10,245 healthy children into a phase 3 clinical trial to evaluate the efficacy of EV71 vaccine in 2012. Fifty subjects from the trial were divided into the potent immune response group (20 subjects) and the ineffective immune response group (30 subjects). Whole-exome...

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PMID: 32531432
DOI: 10.1016/j.ijid.2020.06.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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