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Article

Association of Toll-like receptor 3 gene polymorphism with the severity of enterovirus 71 infection in Chinese children.

Archives of virology - 1 Jun 2017

He Hongfang, Liu Shihai, Liu Pei-Pei, Li Qiu-Bo, Tan Yu-Xia, Guo Ya, Li Fei, Wang Yuan-Yuan, Liu Ye-Dan, Yang Cheng-Qing, Chen Zong-Bo

Abstract excerpt

Enterovirus 71 (EV71) infection has become one of the major threats to children globally in recent years. Toll-like receptor 3 (TLR3) plays an essential role in host defense against EV71 infection. This study was designed to assess the possible association between the TLR3c.1377C/T polymorphism and disease severity in Chinese children with EV71 infection. The TLR3c.1377C/T gene polymorphism was identified in...

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PMID: 28190199
DOI: 10.1007/s00705-017-3265-9

Genes

TLR3

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