Article
Correlation between TLR4 gene polymorphism and severe enterovirus 71 infection.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Oct 2020
Chen Zhenzhen, Zhao Na, Dai Yulong, Chen Zongbo
Abstract excerpt
OBJECTIVE: Enterovirus 71 (EV71) infection resulted in high mortality and disability in children. Immune response deficiency and cytokine genetic predispositions were associated with the severity of EV71 infection. We aim to evaluate the association between TLR4 gene polymorphisms and severity of EV71 infection in Chinese children. METHODS: TLR4 gene polymorphisms were detected through improved multiplex ligation...
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