Article
TMEM173 rs7447927 genetic polymorphism and susceptibility to severe enterovirus 71 infection in Chinese children.
Immunity, inflammation and disease - 1 Dec 2022
Song Jie, Liu Yedan, Guo Ya, Qu Zhenghai, Liu Peipei, Li Fei, Yang Chengqing, Fan Fan, Chen Zongbo
Abstract excerpt
INTRODUCTION: This study was designed to explore the association between the TMEM173 polymorphism (rs7447927) and the severity of enterovirus 71 (EV71) infection among Chinese children. METHODS: The TMEM173 polymorphism was identified in EV71-infected patients (n = 497) and healthy controls (n = 535) using the improved multiplex ligation detection reaction (iMLDR). The interferon-α (IFN-α) serum levels were...
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