Article
A functional polymorphism in IFNAR1 gene is associated with susceptibility and severity of HFMD with EV71 infection.
Scientific reports - 18 Dec 2015
Zou Rongrong, Zhang Guoliang, Li Shaoyuan, Wang Wenfei, Yuan Jing, Li Jianming, Wang Yanrong, Lin Yimin, Deng Yong, Zhou Boping, Gao George Fu, Liu Yingxia
Abstract excerpt
Enterovirus 71 (EV71), one of the major pathogens of Hand, foot and mouth disease (HFMD), results in millions of infections and hundreds of deaths each year in Southeast Asia. Biased infection and variable clinical manifestations of EV71 HFMD indicated that host genetic background played an important role in the occurrence and development of the disease. We identified the mRNA profiles of EV71 HFMD patients,...
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