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Article

Association of the OAS3 rs1859330 G/A genetic polymorphism with severity of enterovirus-71 infection in Chinese Han children.

Archives of virology - 1 Aug 2017

Tan Yuxia, Yang Tingting, Liu Peipei, Chen Liping, Tian Qingwu, Guo Ya, He Hongfang, Liu Yedan, Chen Zongbo

Abstract excerpt

The 2'5'-oligoadenylate synthetase (OAS) is an interferon (IFN)-induced protein that plays an important role in the antiviral action of IFN, with OAS3 being one of the four OAS classes (OAS1, OAS2, OAS3, OASL). The effect of OAS on several infectious viral diseases has been reported; however, a study of the effect of OAS3 on enterovirus 71 (EV71) is lacking. The purpose of this study was to evaluate the...

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Source

Identifiers

PMID: 28444539
DOI: 10.1007/s00705-017-3381-6

Genes

OAS3
CRP
OAS1
OAS2
OASL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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