Article
The cross-neutralizing activity of enterovirus 71 subgenotype c4 vaccines in healthy chinese infants and children.
PloS one - 1 Jan 2013
Mao Qunying, Cheng Tong, Zhu Fengcai, Li Jingxin, Wang Yiping, Li Yanping, Gao Fan, Yang Lisheng, Yao Xin, Shao Jie, Xia Ningshao, Liang Zhenglun, Wang Junzhi
Abstract excerpt
BACKGROUND: EV71 is one of major etiologic causes of hand-foot-mouth disease (HFMD) and leads to severe neurological complications in young children and infants. Recently inactivated EV71 vaccines have been developed by five manufactures and clinically show good safety and immunogenicity. However, the cross-neutralizing activity of these vaccines remains unclear, and is of particular interest because RNA...
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