Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the IRAK4 rs4251545 genetic polymorphism with severity of enterovirus-71 infection in Chinese children.

Immunity, inflammation and disease - 1 May 2022

Song Jie, Liu Yedan, Guo Ya, Liu Peipei, Li Fei, Yang Chengqing, Pan Xiaoyu, Yi Liping, Fan Fan, Zhao Han, Chen Zongbo

Abstract excerpt

INTRODUCTION: This study aimed to explore the association between the IRAK4 polymorphism rs4251545 and the severity of enterovirus 71 (EV71) infection in Chinese children. METHODS: We analyzed the IRAK4 polymorphism rs4251545 in 617 EV71-infected patients and 410 controls using the improved multiplex ligation detection reaction. IRAK4 mRNA expression was tested by qRT-PCR. Serum concentrations of IL-6 and NF-κB...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child
Share to China
Share to Enterovirus A, Human
Share to Enterovirus Infections
Share to Interleukin-1 Receptor-Associated Kinases
Share to Interleukin-6
Share to NF-kappa B
Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 35478439
DOI: 10.1002/iid3.614
PMCID: PMC9017637

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the IRAK4 rs4251545 genetic polymorphism with severity of enterovirus-71 infection in Chinese children.PMID 35478439Read ↗

Correlation between TLR4 gene polymorphism and severe enterovirus 71 infection.Semantic proximity Read ↗

TMEM173 rs7447927 genetic polymorphism and susceptibility to severe enterovirus 71 infection in Chinese children.Semantic proximity Read ↗

Correlation of an interleukin-4 gene polymorphism with susceptibility to severe enterovirus 71 infection in Chinese children.Semantic proximity Read ↗

Association of Toll-like receptor 3 gene polymorphism with the severity of enterovirus 71 infection in Chinese children.Semantic proximity Read ↗

Impact of IL-8-251A/T gene polymorphism on severity of disease caused by enterovirus 71 infection.Semantic proximity Read ↗

Genetic polymorphism of CCL2-2518, CXCL10-201, IL8+781 and susceptibility to severity of Enterovirus-71 infection in a Chinese population.Semantic proximity Read ↗

Oligoadenylate synthetase 3 S381R gene polymorphism is associated with severity of EV71 infection in Chinese children.Semantic proximity Read ↗

IL-10-592 polymorphism is associated with IL-10 expression and severity of enterovirus 71 infection in chinese children.Semantic proximity Read ↗

Relationship between interleukin-18-607C/A gene polymorphism and severity of enterovirus-71 encephalitis in Chinese childrenSemantic proximity Read ↗

A polymorphism in melanoma differentiation-associated gene 5 may be a risk factor for enterovirus 71 infection.Semantic proximity Read ↗

A functional polymorphism in IFNAR1 gene is associated with susceptibility and severity of HFMD with EV71 infection.Semantic proximity Read ↗

Association of Interleukin-17F gene polymorphisms with susceptibility to severe enterovirus 71 infection in Chinese children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.