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Article

Oligoadenylate synthetase 3 S381R gene polymorphism is associated with severity of EV71 infection in Chinese children.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2018

Liu Yedan, Liu Peipei, Liu Shihai, Guo Ya, He Hongfang, Yang Chengqing, Song Jie, Zhang Na, Cheng Jianguo, Chen Zongbo

Abstract excerpt

BACKGROUND: Oligoadenylate synthetase 3 (OAS3) is interferon-induced antiviral enzyme, playing a significant role in the innate immune response. Genetic polymorphism in OAS3 gene has been reported to be a susceptibility factor in many infected diseases, but evidence of its effect on enterovirus 71 (EV71) infection is still lacking. OBJECTIVES: An attempt study was made to investigate whether genetic polymorphism...

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Identifiers

PMID: 29414184
DOI: 10.1016/j.jcv.2018.01.015

Genes

OAS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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