Minimum error correction-based haplotype assembly: Considerations for long read data.

doi:10.1371/journal.pone.0234470

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Article

Minimum error correction-based haplotype assembly: Considerations for long read data.

PloS one - 1 Jan 2020

Majidian Sina, Kahaei Mohammad Hossein, de Ridder Dick

Abstract excerpt

The single nucleotide polymorphism (SNP) is the most widely studied type of genetic variation. A haplotype is defined as the sequence of alleles at SNP sites on each haploid chromosome. Haplotype information is essential in unravelling the genome-phenotype association. Haplotype assembly is a wel...

Topics

Data Analysis
Electronic Data Processing
Genome, Human
Haplotypes
Humans
Polymorphism, Single Nucleotide
Scientific Experimental Error
Sequence Analysis, DNA

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