Haplotype reconstruction from SNP fragments by minimum error correction.

doi:10.1093/bioinformatics/bti352

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Article

Haplotype reconstruction from SNP fragments by minimum error correction.

Bioinformatics (Oxford, England) - 15 May 2005

Wang Rui-Sheng, Wu Ling-Yun, Li Zhen-Ping, Zhang Xiang-Sun

Abstract excerpt

MOTIVATION: Haplotype reconstruction based on aligned single nucleotide polymorphism (SNP) fragments is to infer a pair of haplotypes from localized polymorphism data gathered through short genome fragment assembly. An important computational model of this problem is the minimum error correction...

Topics

Algorithms
Chromosome Mapping
Computer Simulation
DNA Mutational Analysis
Genome, Human
Haplotypes
Humans
Models, Genetic
Models, Statistical
Phylogeny
Polymorphism, Single Nucleotide
Sequence Alignment
Sequence Analysis, DNA

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