Article
Haplotype reconstruction from SNP fragments by minimum error correction.
Bioinformatics (Oxford, England) - 15 May 2005
Wang Rui-Sheng, Wu Ling-Yun, Li Zhen-Ping, Zhang Xiang-Sun
Abstract excerpt
MOTIVATION: Haplotype reconstruction based on aligned single nucleotide polymorphism (SNP) fragments is to infer a pair of haplotypes from localized polymorphism data gathered through short genome fragment assembly. An important computational model of this problem is the minimum error correction (MEC) model, which has been mentioned in several literatures. The model retrieves a pair of haplotypes by correcting...
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