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Computational Methods for Chromosome-Scale Haplotype Reconstruction

2021-01-06

Abstract excerpt

High-quality chromosome-scale haplotype sequences— of diploid genomes, polyploid genomes and metagenomes — provide important insights into genetic variation associated with disease and biodiversity. However, whole-genome short read sequencing does not yield haplotype information that spans whole chromosomes directly. Computational assembly of shorter haplotype fragments is required for haplotype recons...

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Literature Corpus work
ced47d68-244f-55b4-9eef-28f4c36ea922
DOI
10.20944/preprints202101.0116.v1
Open publication

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Computational Methods for Chromosome-Scale Haplotype ReconstructionDOI 10.20944/preprints202101.0116.v1
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