Article

MAtCHap: an ultra fast algorithm for solving the single individual haplotype assembly problem

2019-12-02

Abstract excerpt

<h4>Background</h4> Human genomes are diploid, which means they have two homologous copies of each chromosome and the assignment of heterozygous variants to each chromosome copy, the haplotype assembly problem, is of fundamental importance for medical and population genetics. While short reads from second generation sequencing platforms drastically limit haplotype reconstruction as the great majority of reads do...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3e8758c7-06c6-50d8-97c9-89e7a58169f9
DOI: 10.1101/860262

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MAtCHap: an ultra fast algorithm for solving the single individual haplotype assembly problemDOI 10.1101/860262Read

Progressive approach for SNP calling and haplotype assembly using single molecular sequencing data.Semantic proximity Read

HySA: A Hybrid Structural variant Assembly approach using next generation and single-molecule sequencing technologiesSemantic proximity Read

A highly accurate heuristic algorithm for the haplotype assembly problem.Semantic proximity Read

WhatsHap: Weighted Haplotype Assembly for Future-Generation Sequencing Reads.Semantic proximity Read

HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long readsSemantic proximity Read

AsmMix: A pipeline for high quality diploid <i>de novo</i> assemblySemantic proximity Read

Human Genome Assembly in 100 MinutesSemantic proximity Read

Accurate chromosome-scale haplotype-resolved assembly of human genomesSemantic proximity Read

HapCHAT: Adaptive haplotype assembly for efficiently leveraging high coverage in long readsSemantic proximity Read

HapAssembler: a web server for haplotype assembly from SNP fragments using genetic algorithm.Semantic proximity Read

Efficient and accurate near telomere-to-telomere haplotype reconstruction of diploid genomesSemantic proximity Read

HapCol: accurate and memory-efficient haplotype assembly from long reads.Semantic proximity Read