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Article

Recurrent Loss of SMARCA4 in Sinonasal Teratocarcinosarcoma

5 Jun 2020

Abstract excerpt

Molecular analysis has reshaped the landscape of high grade sinonasal tumors by defining novel entities and identifying recurrent mutations in established tumor types. However, sinonasal teratocarcinosarcoma (TCS), a rare and aggressive tumor with intermixed teratomatous, carcinomatous, and sarcomatous elements, remains poorly understood. The multiphenotypic differentiation of TCS has engendered persistent...

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PMID: 32520761
DOI: 10.1097/pas.0000000000001508

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