Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SMARCB1 -deficient Tumors of Childhood: A Practical Guide

27 Dec 2017

Abstract excerpt

The SMARCB1 gene ( INI1, BAF47) is a member of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex, involved in the epigenetic regulation of gene transcription. SMARCB1 acts as a tumor suppressor gene, and loss of function of both alleles gives rise to SMARCB1-deficient tumors. The prototypical SMARCB1-deficient tumor is the malignant rhabdoid tumor (MRT) which was first described in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Chromatin Remodeling and Cancer
Share to Tumors and Oncological Cases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29280680
DOI: 10.1177/1093526617749671

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SMARCB1 -deficient Tumors of Childhood: A Practical GuidePMID 29280680Read ↗

The expanding family of SMARCB1(INI1)-deficient neoplasia: implications of phenotypic, biological, and molecular heterogeneity.Semantic proximity Read ↗

Pathology and diagnosis of SMARCB1-deficient tumors.Semantic proximity Read ↗

SMARCB1/INI1-deficient tumors of adulthoodSemantic proximity Read ↗

SMARCB1/INI1-deficient tumors of adulthoodSemantic proximity Read ↗

Advancing biology-based therapeutic approaches for atypical teratoid rhabdoid tumorsSemantic proximity Read ↗

Primary adult sellar SMARCB1/INI1-deficient tumor represents a subtype of atypical teratoid/rhabdoid tumorSemantic proximity Read ↗

Development and epigenetic regulation of Atypical teratoid/rhabdoid tumors in the context of cell-of-origin and halted cell differentiationSemantic proximity Read ↗

Immunotherapy for SMARCB1-Deficient Sarcomas: Current Evidence and Future DevelopmentsSemantic proximity Read ↗

Rhabdoid tumor predisposition syndrome.Semantic proximity Read ↗

SMARCB1-related schwannomatosis and other SMARCB1-associated phenotypes: clinical spectrum and molecular pathogenesis.Semantic proximity Read ↗

Consistent <i>SMARCB1</i> homozygous deletions in epithelioid sarcoma and in a subset of myoepithelial carcinomas can be reliably detected by FISH in archival materialSemantic proximity Read ↗

Biology and Treatment of Rhabdoid TumorSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.