Article
Clinicopathological and molecular characterization of SMARCA4-deficient thoracic sarcomas with comparison to potentially related entities.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2017
Yoshida Akihiko, Kobayashi Eisuke, Kubo Takashi, Kodaira Makoto, Motoi Toru, Motoi Noriko, Yonemori Kan, Ohe Yuichiro, Watanabe Shun-Ichi, Kawai Akira, Kohno Takashi, Kishimoto Hiroshi, Ichikawa Hitoshi, Hiraoka Nobuyoshi
Abstract excerpt
A growing number of studies suggest critical tumor suppressor roles of the SWI/SNF chromatin remodeling complex in a variety of human cancers. The recent discovery of SMARCA4-deficient thoracic sarcomas has added to the list of tumor groups with the SMARCA4 inactivating mutation. To better characterize these tumors and establish their nosological status, we undertook a clinicopathological and molecular analysis...
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