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Article

Genetic basis of SMARCB1 protein loss in 22 sinonasal carcinomas.

Human pathology - 1 Oct 2020

Dogan Snjezana, Cotzia Paolo, Ptashkin Ryan N, Nanjangud Gouri J, Xu Bin, Momeni Boroujeni Amir, Cohen Marc A, Pfister David G, Prasad Manju L, Antonescu Cristina R, Chen Yingbei, Gounder Mrinal M

Abstract excerpt

SMARCB1-deficient sinonasal carcinoma (SNC) is an aggressive malignancy characterized by INI1 loss mostly owing to homozygous SMARCB1 deletion. With the exception of a few reported cases, these tumors have not been thoroughly studied by massive parallel sequencing (MPS). A retrospective cohort of 22 SMARCB1-deficient SNCs were studied by light microscopy, immunohistochemistry, fluorescence in situ hybridization...

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Identifiers

PMID: 32818509
DOI: 10.1016/j.humpath.2020.08.004
PMCID: PMC7669579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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