Article
In vivo histopathological staging in C9orf72-associated ALS: A tract of interest DTI study.
NeuroImage. Clinical - 1 Jan 2020
Müller Hans-Peter, Del Tredici Kelly, Lulé Dorothée, Müller Kathrin, Weishaupt Jochen H, Ludolph Albert C, Kassubek Jan
Abstract excerpt
BACKGROUND: Diffusion tensor imaging (DTI) can identify amyotrophic lateral sclerosis (ALS)-associated patterns of brain alterations at the group level according to a neuropathological staging system. OBJECTIVE: The study was designed to investigate the in vivo staging in ALS patients with the C9orf72 expansion and potential differences to ALS patients with the SOD1 mutation. METHODS: DTI-based white matter...
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