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Article

In Vivo Evaluation of White Matter Abnormalities in Children with Duchenne Muscular Dystrophy Using DTI.

AJNR. American journal of neuroradiology - 1 Jul 2020

Preethish-Kumar V, Shah A, Kumar M, Ingalhalikar M, Polavarapu K, Afsar M, Rajeswaran J, Vengalil S, Nashi S, Thomas P T, Sadasivan A, Warrier M, Nalini A, Saini J

Abstract excerpt

BACKGROUND AND PURPOSE: Duchenne muscular dystrophy is an X-linked disorder characterized by progressive muscle weakness and prominent nonmotor manifestations, such as a low intelligence quotient and neuropsychiatric disturbance. We investigated WM integrity in patients with Duchenne muscular dystrophy using DTI. MATERIALS AND METHODS: Fractional anisotropy and mean, axial, and radial diffusivity (DTI measures)...

Topics

Adolescent
Brain
Child
Diffusion Tensor Imaging
Dystrophin
Female
Humans
Male
Muscular Dystrophy, Duchenne
Mutation
Neuroimaging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

White Matter

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Identifiers

PMID: 32616576
DOI: 10.3174/ajnr.A6604
PMCID: PMC7357653

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