Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between rs1799971 in the mu opioid receptor gene and methadone maintenance treatment response.

Journal of clinical laboratory analysis - 1 Nov 2022

Xie Xiaohu, Gu Jun, Zhuang Dingding, Zhou Yun, Chen Xiaoyu, Shen Wenwen, Li Longhui, Liu Yue, Xu Wenjin, Hong Qingxiao, Xu Zemin, Chen Weisheng, Zhou Wenhua, Liu Huifen

Abstract excerpt

OBJECTIVE: Genetic variations can affect individual response to methadone maintenance treatment (MMT) for heroin addiction. The A118G variant (rs1799971) in the mu opioid receptor gene (OPRM1) is a potential candidate single nucleotide polymorphism (SNP) for personalized MMT. This study determined whether rs1799971 is related to MMT response or dose. METHODS: We recruited 286 MMT patients from a Han Chinese...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype
Share to Heroin Dependence
Share to Methadone
Share to Neuropeptides and Animal Physiology
Share to Pain Management and Opioid Use
Share to Polymorphism, Single Nucleotide
Share to Receptors, Opioid, mu

Source

Open in PubMed Open full text

Identifiers

PMID: 36305091
DOI: 10.1002/jcla.24750
PMCID: PMC9701885

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between rs1799971 in the mu opioid receptor gene and methadone maintenance treatment response.PMID 36305091Read ↗

The impact of OPRM1's genetic polymorphisms on methadone maintenance treatment in opioid addicts: a systematic review.Semantic proximity Read ↗

Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1.Semantic proximity Read ↗

Genetic polymorphisms in the opioid receptor mu1 gene are associated with changes in libido and insomnia in methadone maintenance patients.Semantic proximity Read ↗

Genetic polymorphisms in the opioid receptor delta 1 (OPRD1) gene are associated with methadone dose in methadone maintenance treatment for heroin dependence.Semantic proximity Read ↗

Association of dopamine and opioid receptor genetic polymorphisms with response to methadone maintenance treatment.Semantic proximity Read ↗

ABCB1, SLC22A1, COMT, and OPRM1 genotypes: Study of their influence on plasma methadone levels and clinical response to methadone maintenance treatment in opioid use disorder.Semantic proximity Read ↗

OPRM1 genetic polymorphisms are associated with the plasma nicotine metabolite cotinine concentration in methadone maintenance patients: a cross sectional study.Semantic proximity Read ↗

κ Opioid Receptor 1 Single Nucleotide Polymorphisms were Associated with the Methadone Dosage.Semantic proximity Read ↗

OPRM1 rs1799971 polymorphism and opioid dependence: evidence from a meta-analysis.Semantic proximity Read ↗

Pharmacogenomics of the human µ-opioid receptor.Semantic proximity Read ↗

OPRM1 and CYP3A4 association with methadone dose in Iranian patients undergoing methadone maintenance therapy.Semantic proximity Read ↗

Precision therapeutic opioid dosing implications from genetic biomarkers and craving score.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.