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Mutational landscape of patients with acute myeloid leukemia or myelodysplastic syndromes in the context of RUNX1 mutation.

Hematology (Amsterdam, Netherlands) - 1 Dec 2020

Wang Kai, Zhou Feng, Cai Xiaohui, Chao Hongying, Zhang Ri, Chen Suning

Abstract excerpt

Introduction: RUNX1 mutations in acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) are associated with distinct clinicopathologic features. However, the clinical and laboratory characteristics of the myeloid malignancies may be inﬂuenced by the presence of more concomitant mutations. The aim of this study is to provide a further understanding of mutational landscape in the context of RUNX1 mutation...

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Young Adult
Adolescent
Core Binding Factor Alpha 2 Subunit
Leukemia, Myeloid, Acute
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Myelodysplastic Syndromes

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PMID: 32476595
DOI: 10.1080/16078454.2020.1765561

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