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Article

Prognostic impact of DTA mutation and co-occurring mutations in patients with myelodysplastic syndrome.

Molecular biology reports - 15 Sept 2024

Wang Min, Chen Ping, Li Daqi, Zhao Mingfeng

Abstract excerpt

OBJECTIVE: To evaluate the frequency and prognostic significance of DTA (DNMT3A、TET2、ASXL1) gene mutation and co-occurring mutations in patients with myelodysplastic syndrome (MDS). METHODS: The clinical data of 102 newly diagnosed MDS patients who accepted Next Generation Sequencing (NGS) was retrospectively analyzed. According to whether the patients had DTA gene mutation, the patients were divided into DTA...

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PMID: 39278886
DOI: 10.1007/s11033-024-09922-7

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