Article
The Genetic Landscape of Myelodysplastic Neoplasm Progression to Acute Myeloid Leukemia.
International journal of molecular sciences - 17 Mar 2023
Bănescu Claudia, Tripon Florin, Muntean Carmen
Abstract excerpt
Myelodysplastic neoplasm (MDS) represents a heterogeneous group of myeloid disorders that originate from the hematopoietic stem and progenitor cells that lead to the development of clonal hematopoiesis. MDS was characterized by an increased risk of transformation into acute myeloid leukemia (AML). In recent years, with the aid of next-generation sequencing (NGS), an increasing number of molecular aberrations were...
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