Article
Co-mutation landscape and clinical significance of RAS pathway related gene mutations in patients with myelodysplastic syndrome.
Hematological oncology - 1 Feb 2023
Ren Yanling, Lang Wei, Mei Chen, Luo Yingwan, Ye Li, Wang Lu, Zhou Xinping, Xu Gaixiang, Ma Liya, Jin Jie, Tong Hongyan
Abstract excerpt
Single gene mutations in the RAS pathway are uncommon and of unknown significance in myelodysplastic syndrome (MDS) patients, RAS pathway-related gene mutations (RASwaymut ) as a whole may be significant and require further elucidation. The clinical and molecular data of 370 MDS patients who were newly diagnosed between 1 November 2016 and 31 August 2020 in our hospital were collected and retrospectively...
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