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Article

Cancer associated fibroblast: Mediators of tumorigenesis.

Matrix biology : journal of the International Society for Matrix Biology - 1 Sept 2020

Alexander Jennifer, Cukierman Edna

Abstract excerpt

It is well accepted that the tumor microenvironment plays a pivotal role in cancer onset, development, and progression. The majority of clinical interventions are designed to target either cancer or stroma cells. These emphases have been directed by one of two prevailing theories in the field, the Somatic Mutation Theory and the Tissue Organization Field Theory, which represent two seemingly opposing concepts....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32450219
DOI: 10.1016/j.matbio.2020.05.004
PMCID: PMC7434664

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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