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Pancreatic Cancer and Its Microenvironment-Recent Advances and Current Controversies.

International journal of molecular sciences - 1 May 2020

Stopa Kinga B, Kusiak Agnieszka A, Szopa Mateusz D, Ferdek Pawel E, Jakubowska Monika A

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) causes annually well over 400,000 deaths world-wide and remains one of the major unresolved health problems. This exocrine pancreatic cancer originates from the mutated epithelial cells: acinar and ductal cells. However, the epithelia-derived cancer component forms only a relatively small fraction of the tumor mass. The majority of the tumor consists of acellular fibrous...

Topics

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Cancer-Associated Fibroblasts
Carcinogens
Carcinoma, Pancreatic Ductal
Disease Susceptibility
Pancreatic Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Stress, Physiological

Tumor Microenvironment

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Identifiers

PMID: 32370075
DOI: 10.3390/ijms21093218
PMCID: PMC7246785

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