[Assessment of mitochondria-associated genes for single nucleotide polymorphisms linked to the development of hypertrophic cardiomyopathy in the senescence-accelerated OXYS rats.]

Abstract excerpt

Hypertrophic cardiomyopathy (HС) is a heterogeneous myocardial disease with a wide range of clinical manifestations and risk of development increasing with age along with myocardial changes characteristic of aging. The contribution of genetic component to the development of HC is obvious, however, the etiology and pathogenesis of this disease remains unclear in 50% of cases. The aim of the present study was to...

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