Article

Senescence-accelerated OXYS rats: A genetic model of premature aging and age-related diseases

2014-10-01

Abstract excerpt

A genetic model of accelerated senescence and the associated diseases in the OXYS strain of rats was established by selection and inbreeding of Wistar rats sensitive to the cataractogenic effects of galactose. In the first five generations, the development of a cataract was induced by galactose overconsumption, and, subsequently, the selection was carried out for early spontaneous cataract, genetically linked with...

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Literature Corpus work: 5cf0b6d3-0ab1-5b3d-83c9-fb31d09ce8ad
DOI: 10.1134/s2079057014040146

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