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Article

Application of quantitative trait locus mapping and transcriptomics to studies of the senescence-accelerated phenotype in rats.

BMC genomics - 1 Jan 2014

Korbolina Elena E, Ershov Nikita I, Bryzgalov Leonid O, Kolosova Natalia G

Abstract excerpt

BACKGROUND: Etiology of complex disorders, such as cataract and neurodegenerative diseases including age-related macular degeneration (AMD), remains poorly understood due to the paucity of animal models, fully replicating the human disease. Previously, two quantitative trait loci (QTLs) associated with early cataract, AMD-like retinopathy, and some behavioral aberrations in senescence-accelerated OXYS rats were...

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Identifiers

PMID: 25563673
DOI: 10.1186/1471-2164-15-S12-S3
PMCID: PMC4303943

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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