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Article

Association of CD40 gene polymorphism (C-1T) with susceptibility and phenotype of Graves' disease.

Thyroid : official journal of the American Thyroid Association - 1 Oct 2005

Kurylowicz Alina, Kula Dorota, Ploski Rafal, Skorka Agata, Jurecka-Lubieniecka Beata, Zebracka Jadwiga, Steinhof-Radwanska Katarzyna, Hasse-Lazar Kornelia, Hiromatsu Yuji, Jarzab Barbara, Bednarczuk Tomasz

Abstract excerpt

OBJECTIVE: Recently, a functional polymorphism in the CD40 gene at position -1, C to T change (C-1T) has been identified and the C/C genotype has been reported to be associated with Graves' disease (GD). DESIGN: We performed a case-control, replication study on 556 patients with GD and 611 healthy subjects in a Polish population. Furthermore, we analyzed the distribution of CD40 genotypes in subgroups of patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16279844
DOI: 10.1089/thy.2005.15.1119

Genes

CTLA4
PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of CD40 gene polymorphism (C-1T) with susceptibility and phenotype of Graves' disease.PMID 16279844Read ↗

A C/T single-nucleotide polymorphism in the region of the CD40 gene is associated with Graves' disease.Semantic proximity Read ↗

A C/T polymorphism in the 5' untranslated region of the CD40 gene is associated with later onset of Graves' disease in Japanese.Semantic proximity Read ↗

Association of a C/T single-nucleotide polymorphism in the 5' untranslated region of the CD40 gene with Graves' disease in Japanese.Semantic proximity Read ↗

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Compelling Evidence Linking CD40 Gene With Graves' Disease in the Chinese Han Population.Semantic proximity Read ↗

A single nucleotide polymorphism in the CD40 gene on chromosome 20q (GD-2) provides no evidence for susceptibility to Graves' disease in UK Caucasians.Semantic proximity Read ↗

Association of CD40 and thyroglobulin genes with later-onset Graves' disease in Taiwanese patients.Semantic proximity Read ↗

Association and linkage studies of the 20q11.2 region (GRD-2 locus) with Graves' disease in the Tunisian population.Semantic proximity Read ↗

CD40 C/T-1 polymorphism plays different roles in Graves' disease and Hashimoto's thyroiditis: a meta-analysis.Semantic proximity Read ↗

Role of Different CD40 Polymorphisms in Graves' Disease and Hashimoto's Thyroiditis.Semantic proximity Read ↗

Polymorphisms of the genes CTLA4, PTPN22, CD40, and PPARG and their roles in Graves' disease: susceptibility and clinical features.Semantic proximity Read ↗

A C/T polymorphism in the 5'-untranslated region of the CD40 gene is associated with Graves' disease in Koreans.Semantic proximity Read ↗

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