Article
Association between age at diagnosis of Graves' disease and variants in genes involved in immune response.
PloS one - 1 Jan 2013
Jurecka-Lubieniecka Beata, Ploski Rafal, Kula Dorota, Krol Aleksandra, Bednarczuk Tomasz, Kolosza Zofia, Tukiendorf Andrzej, Szpak-Ulczok Sylwia, Stanjek-Cichoracka Anita, Polanska Joanna, Jarzab Barbara
Abstract excerpt
BACKGROUND: Graves' disease (GD) is a complex disease in which genetic predisposition is modified by environmental factors. The aim of the study was to examine the association between genetic variants in genes encoding proteins involved in immune response and the age at diagnosis of GD. METHODS: 735 GD patients and 1216 healthy controls from Poland were included into the study. Eight genetic variants in the...
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