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Article

High Levels of Chromosomal Copy Number Alterations and TP53 Mutations Correlate with Poor Outcome in Younger Breast Cancer Patients.

The American journal of pathology - 1 Aug 2020

Koçak Ayla, Heselmeyer-Haddad Kerstin, Lischka Annette, Hirsch Daniela, Fiedler David, Hu Yue, Doberstein Natalie, Torres Irianna, Chen Wei-Dong, Gertz E Michael, Schäffer Alejandro A, Freitag-Wolf Sandra, Kirfel Jutta, Auer Gert, Habermann Jens K, Ried Thomas

Abstract excerpt

Prognosis in young patients with breast cancer is generally poor, yet considerable differences in clinical outcomes between individual patients exist. To understand the genetic basis of the disparate clinical courses, tumors were collected from 34 younger women, 17 with good and 17 with poor outcomes, as determined by disease-specific survival during a follow-up period of 17 years. The clinicopathologic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32416097
DOI: 10.1016/j.ajpath.2020.04.015
PMCID: PMC7397461

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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