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Article

Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival.

Proceedings of the National Academy of Sciences of the United States of America - 3 Jul 2001

Jain A N, Chin K, Børresen-Dale A L, Erikstein B K, Eynstein Lonning P, Kaaresen R, Gray J W

Abstract excerpt

We present a general method for rigorously identifying correlations between variations in large-scale molecular profiles and outcomes and apply it to chromosomal comparative genomic hybridization data from a set of 52 breast tumors. We identify two loci where copy number abnormalities are correlated with poor survival outcome (gain at 8q24 and loss at 9q13). We also identify a relationship between abnormalities...

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Identifiers

PMID: 11438741
DOI: 10.1073/pnas.151241198
PMCID: PMC35449

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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