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Article

Copy number alterations that predict metastatic capability of human breast cancer.

Cancer research - 1 May 2009

Zhang Yi, Martens John W M, Yu Jack X, Jiang John, Sieuwerts Anieta M, Smid Marcel, Klijn Jan G M, Wang Yixin, Foekens John A

Abstract excerpt

We have analyzed the DNA copy numbers for over 100,000 single-nucleotide polymorphism loci across the human genome in genomic DNA from 313 lymph node-negative primary breast tumors for which genome-wide gene expression data were also available. Combining these two data sets allowed us to identify the genomic loci and their mapped genes, having high correlation with distant metastasis. An estimation of the likely...

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PMID: 19336569
DOI: 10.1158/0008-5472.CAN-08-4596

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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