Article

Targeting genomic instability using a genomic and proteomic approach to identify molecular drivers of poor prognosis in cancer

2017-01-01

Abstract excerpt

Cancer is a disease of the genome whereby mutational events that confer a survival advantage to cells are selectively retained. Consequently, genome instability and evasion of cell death are fundamental hallmarks of cancer. Certain cancers, including epithelial ovarian cancers (EOC), pancreatic ductal adenocarcinomas (PDAC) and a subset of sarcomas with complex karyotypes are characterized as being very genomicall...

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Literature Corpus work: 96cbeb98-4bd2-5452-abcb-a65b391feda1
DOI: 10.25560/55989

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