Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of COMT Gene Polymorphisms with Response to Methadone Maintenance Treatment Among Chinese Opioid-Dependent Patients.

Genetic testing and molecular biomarkers - 1 Jun 2020

Duan Luxi, Li Xingyuan, Yan Junxia, Chen Yingyi, Luo Rui, Zhang Qiang, Feng Xiangling, Li Xingli

Abstract excerpt

Aim: To explore the association of the COMT gene polymorphisms (rs4680, rs737866, and rs933271) with the response to methadone maintenance treatment (MMT) among Chinese opioid-dependent patients. Methods: A total of 820 patients who were receiving MMT from Chinese clinics were recruited. Questionnaires were used to collect patient information, including sociodemographics, history of drug use, and stable methadone...

Read the complete abstract on PubMed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analgesics, Opioid
Share to Asian People
Share to Biomarkers, Pharmacological
Share to Catechol O-Methyltransferase
Share to Gene Expression Regulation
Share to Methadone
Share to Odds Ratio
Share to Opioid-Related Disorders

Source

Identifiers

PMID: 32407152
DOI: 10.1089/gtmb.2019.0275

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of COMT Gene Polymorphisms with Response to Methadone Maintenance Treatment Among Chinese Opioid-Dependent Patients.PMID 32407152Read ↗

Association between a COMT polymorphism and clinical response to risperidone treatment: a pharmacogenetic study.Semantic proximity Read ↗

Association studies of catechol-O-methyltransferase (COMT) gene with schizophrenia and response to antipsychotic treatment.Semantic proximity Read ↗

ABCB1, SLC22A1, COMT, and OPRM1 genotypes: Study of their influence on plasma methadone levels and clinical response to methadone maintenance treatment in opioid use disorder.Semantic proximity Read ↗

OPRM1 genetic polymorphisms are associated with the plasma nicotine metabolite cotinine concentration in methadone maintenance patients: a cross sectional study.Semantic proximity Read ↗

Association of the OPRM1 and COMT genes' polymorphisms with the efficacy of morphine in Tunisian cancer patients: Impact of the high genetic heterogeneity in Tunisia?Semantic proximity Read ↗

Genetic variations in catechol-O-methyltransferase gene are associated with levodopa response variability in Chinese patients with Parkinson's disease.Semantic proximity Read ↗

Prospective replication study implicates the catechol-O-methyltransferase Val158Met polymorphism as a biomarker for the response to morphine in patients with cancerSemantic proximity Read ↗

Association between rs1799971 in the mu opioid receptor gene and methadone maintenance treatment response.Semantic proximity Read ↗

Significant Association of the Catechol-O-Methyltransferase Gene Polymorphism (rs4680) and Opioid Use Disorder in Asian Populations, but not Caucasian Populations: A Meta-analysis.Semantic proximity Read ↗

Catechol-O-methyltransferase (COMT) polymorphisms predict treatment response in electroconvulsive therapySemantic proximity Read ↗

Association between catechol-O-methyltransferase (COMT) Val/Met genotype and smoking cessation treatment with nicotine: a meta-analysis.Semantic proximity Read ↗

Genetic polymorphisms in the opioid receptor delta 1 (OPRD1) gene are associated with methadone dose in methadone maintenance treatment for heroin dependence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.