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Article

OPRM1 genetic polymorphisms are associated with the plasma nicotine metabolite cotinine concentration in methadone maintenance patients: a cross sectional study.

Journal of human genetics - 1 Feb 2013

Chen Yu-Ting, Tsou Hsiao-Hui, Kuo Hsiang-Wei, Fang Chiu-Ping, Wang Sheng-Chang, Ho Ing-Kang, Chang Yao-Sheng, Chen Chia-Hui, Hsiao Chin-Fu, Wu Hsiao-Yu, Lin Keh-Ming, Chen Andrew Ch, Tsai-Wu Jyy-Jih, Liu Yu-Li

Abstract excerpt

Majority of the heroin-dependent patients smoke cigarettes. Although it has been reported that the OPRM1 genetic polymorphism is associated with the brain mu-opioid receptor binding potential in cigarette smokers, there is no direct evidence showing the impact of plasma cotinine, a nicotine metabolite, on treatment responses to methadone maintenance treatment (MMT). In this study, we aimed to test the hypothesis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23223006
DOI: 10.1038/jhg.2012.139

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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OPRM1 genetic polymorphisms are associated with the plasma nicotine metabolite cotinine concentration in methadone maintenance patients: a cross sectional study.PMID 23223006Read ↗

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