Article
Significant Association of the Catechol-O-Methyltransferase Gene Polymorphism (rs4680) and Opioid Use Disorder in Asian Populations, but not Caucasian Populations: A Meta-analysis.
Genetic testing and molecular biomarkers - 1 Jun 2022
Huang Xiaohui, Wang Changwang, Zheng Li, Ren Lei, Jin Tao, Yu Zeqing, Tang Yanxia
Abstract excerpt
Objective: Previous studies have reported on the association between the rs4680 polymorphism in the Catechol-O-methyltransferase (COMT) gene and opioid use disorder (OUD) with inconsistent outcomes. The goal of this study was to examine the correlation of the rs4680 polymorphism and OUD using a meta-analysis approach. Methods: Six electronic databases, including PubMed, Web of Science, Cochrane Library, EMBASE,...
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