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Article

Impact of genetic predisposition to late-onset neurodegenerative diseases on early life outcomes and brain structure.

Translational psychiatry - 11 Apr 2024

Ogonowski Natalia S, García-Marín Luis M, Fernando Amali S, Flores-Ocampo Victor, Rentería Miguel E

Abstract excerpt

Most patients with late-onset neurodegenerative diseases such as Alzheimer's and Parkinson's have a complex aetiology resulting from numerous genetic risk variants of small effects located across the genome, environmental factors, and the interaction between genes and environment. Over the last decade, genome-wide association studies (GWAS) and post-GWAS analyses have shed light on the polygenic architecture of...

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Identifiers

PMID: 38605018
DOI: 10.1038/s41398-024-02898-9
PMCID: PMC11009228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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