Article
Platelet Integrin αIIbβ3 Activation is Associated with 25-Hydroxyvitamin D Concentrations in Healthy Adults.
Thrombosis and haemostasis - 1 May 2020
Aleva Floor E, Tunjungputri Rahajeng N, van der Vorm Lisa N, Li Yang, Heijdra Yvonne F, Oosting Marije, Smeekens Sanne P, Jaeger Martin, Joosten Leo A B, de Groot Philip G, Netea Mihai G, van der Ven Andre J A M, de Mast Quirijn
Abstract excerpt
BACKGROUND: Cardiovascular events are associated with low circulating vitamin D concentrations, although the underlying mechanisms are poorly understood. This study investigated associations between 25-hydroxyvitamin D concentrations, platelet function, and single-nucleotide polymorphisms (SNPs) in genes influencing vitamin D biology in the 500 Functional Genomics (500FG) cohort. METHODS: In this observational...
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